Iron(III) tetrakis(pentafluorophenyl)porpholactone catalyzes nitrogen atom transfer to C=C and C-H bonds with organic azides.

نویسندگان

  • Lei Liang
  • Hongbin Lv
  • Yi Yu
  • Peng Wang
  • Jun-Long Zhang
چکیده

We have demonstrated that iron porpholactones could be effective catalysts for nitrogen atom transfer reactions such as aziridination of alkenes and amidation of alkanes using organic azides.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Nitrene Radical Intermediates in Catalytic Synthesis

Nitrene radical complexes are reactive intermediates with discrete spin density at the nitrogen-atom of the nitrene moiety. These species have become important intermediates for organic synthesis, being invoked in a broad range of C-H functionalization and aziridination reactions. Nitrene radical complexes have intriguing electronic structures, and are best described as one-electron reduced Fis...

متن کامل

Cytochrome P450-catalyzed dealkylation of atrazine by Rhodococcus sp. strain NI86/21 involves hydrogen atom transfer rather than single electron transfer.

Cytochrome P450 enzymes are responsible for a multitude of natural transformation reactions. For oxidative N-dealkylation, single electron (SET) and hydrogen atom abstraction (HAT) have been debated as underlying mechanisms. Combined evidence from (i) product distribution and (ii) isotope effects indicate that HAT, rather than SET, initiates N-dealkylation of atrazine to desethyl- and desisopro...

متن کامل

Late Stage Azidation of Complex Molecules

Selective functionalization of complex scaffolds is a promising approach to alter the pharmacological profiles of natural products and their derivatives. We report the site-selective azidation of benzylic and aliphatic C-H bonds in complex molecules catalyzed by the combination of Fe(OAc)2 and a PyBox ligand. The same system also catalyzes the trifluoromethyl azidation of olefins to form deriva...

متن کامل

HIGHLIGHT Cyclic Hypervalent Iodine Reagents and Iron Catalysis: the Winning Team for Late-Stage C-H Azidation

In the past decades azides have received increasing attention due to their exceptional reactivity and versatility in organic chemistry. Their use as non-basic precursors of amines or their easy conversion to nitrene intermediates for further C-N bond transformations made them key building blocks in chemistry, biology and material science. In spite of their hailed synthetic utility, their instal...

متن کامل

Metalloporphyrin-catalysed epoxidation using hydrogen peroxide

The catalysis by S, 1 0, IS,20-tetrakis(pentafluorophenyl)-21H,23H-porphyrin iron(III) chloride (F20 TPPFeCl) of alkene epoxidation by H20 2 has been investigated. Extensive catalyst decomposition was observed during the reaction. A kinetics and product yield analysis has shown that this decomposition does not occur via either the oxoperferryl intermediate (F 20 TPP·+)F e =0 or the oxoferryl in...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Dalton transactions

دوره 41 5  شماره 

صفحات  -

تاریخ انتشار 2012